SUPREME-DM - Home
SURVEILLANCE, PREVENTION, AND MANAGEMENT OF DIABETES MELLITUS
(SUPREME-DM)
The overall goal of this Agency for Healthcare Research and Quality (AHRQ)-funded project, conducted 2010 through 2013, was to develop a comprehensive, longitudinal clinical registry of a population of approximately 1.3 million insured patients with diabetes mellitus, and a similar database of all members without diabetes from 11 integrated healthcare delivery systems. The registry, or DataLink, covers the period from 2005-2011, draws from demographic and clinical data elements in Electronic Health Records (EHRs) and other system databases, and adds calculated data on medication adherence. The multi-disciplinary SUPREME-DM Network was comprised of nearly 30 diabetes researchers from both the HMO Research Network and academic centers. They worked to build and maintain the data infrastructure while conducting studies to demonstrate the capacity of the data link for conducting diabetes surveillance.
In addition, SUPREME-DM conducted two comparative effectiveness research (CER) studies: a trial to evaluate the effectiveness of brief counseling on “early non-adherence” with newly prescribed medications; and an observational study of women with recent gestational diabetes to understand the effectiveness of various communication, counseling, and referral strategies. Patient-reported and natural language processing (NLP)-derived measures were also examined as potential mediators or modifiers of treatment effectiveness in both CER studies.
Please click on the Publications tab to access articles that contain study results.
In September 2013, the SUPREME-DM Network was awarded additional funding from AHRQ to:
collaborate with a broad array of stakeholders to prioritize critical themes and topics for CER and patient-centered outcomes research (PCOR) to prevent and treat diabetes;
develop and test specific enhancements to the SUPREME-DM DataLink that expand its capacity to address stakeholder priorities for research to improve diabetes prevention and treatment; and
develop a 5-year plan to sustain the capacity of the SUPREME-DM Network and its DataLink to address high-priority themes and topics for CER and PCOR.
The SUPREME-DM DataLink is a distributed data set. Participating sites have a common data model based on the HMO Research Network's Virtual Data Warehouse. SAS programming code is developed and distributed to participating sites. The code is executed and results are returned to the site leading a particular analysis. Data are only generated and shared when there is a project of interest to the investigator team, when there is funding to conduct the work, and all IRB approvals and data agreements are in place. The SUPREME-DM DataLink is not for sale or distributed for public use. The SUPREME-DM investigators, however, welcome requests for public domain research collaboration. Feel free to access the Contact tab to send us an email.
(SUPREME-DM)
The overall goal of this Agency for Healthcare Research and Quality (AHRQ)-funded project, conducted 2010 through 2013, was to develop a comprehensive, longitudinal clinical registry of a population of approximately 1.3 million insured patients with diabetes mellitus, and a similar database of all members without diabetes from 11 integrated healthcare delivery systems. The registry, or DataLink, covers the period from 2005-2011, draws from demographic and clinical data elements in Electronic Health Records (EHRs) and other system databases, and adds calculated data on medication adherence. The multi-disciplinary SUPREME-DM Network was comprised of nearly 30 diabetes researchers from both the HMO Research Network and academic centers. They worked to build and maintain the data infrastructure while conducting studies to demonstrate the capacity of the data link for conducting diabetes surveillance.
In addition, SUPREME-DM conducted two comparative effectiveness research (CER) studies: a trial to evaluate the effectiveness of brief counseling on “early non-adherence” with newly prescribed medications; and an observational study of women with recent gestational diabetes to understand the effectiveness of various communication, counseling, and referral strategies. Patient-reported and natural language processing (NLP)-derived measures were also examined as potential mediators or modifiers of treatment effectiveness in both CER studies.
Please click on the Publications tab to access articles that contain study results.
In September 2013, the SUPREME-DM Network was awarded additional funding from AHRQ to:
The SUPREME-DM DataLink is a distributed data set. Participating sites have a common data model based on the HMO Research Network's Virtual Data Warehouse. SAS programming code is developed and distributed to participating sites. The code is executed and results are returned to the site leading a particular analysis. Data are only generated and shared when there is a project of interest to the investigator team, when there is funding to conduct the work, and all IRB approvals and data agreements are in place. The SUPREME-DM DataLink is not for sale or distributed for public use. The SUPREME-DM investigators, however, welcome requests for public domain research collaboration. Feel free to access the Contact tab to send us an email.